Since Yahweh alone saves, people and nations around the world should turn to Him for salvation (cf. Numbers 21:8-9). In so doing they could experience the same salvation that Israel would enjoy. Yahweh is the saving God of the whole earth, not just Israel, so salvation is available to all, not just Israel. God used this verse to bring the light of salvation to the English preacher Charles Haddon Spurgeon when he was a youth. [source][source][source]
Context Summary
Isaiah 45:14-25 - A Call To The Ends Of The Earth
As the prophet reviews God's method of delivering His people-so unexpected and so wonderful-he cannot restrain the ejaculation: Thou art a God that hidest thyself! "Deep in unfathomable mines of never-failing skill, He treasures up His bright designs and works His sovereign will." You do not see how God is going to save you; but most certainly His Angel will redeem you from all evil.
God contrasts Himself with idols, Isaiah 45:20. We can never seek His face in vain. They that trust in man or their own devices are doomed to disappointment; but faith and prayer make all the difference. He is "a just God and a Savior." This is the wonderful combination that the Cross reveals. See Romans 3:26; 1 John 1:9. Look to Him and be saved. Even if you dwell in a far land or at the ends of the earth, and even if you can only look toward Him with failing sight, remember that "there is life in a look." Dare to say, "In the Lord have I righteousness and strength." You have none of your own! Your strength is weakness! Your righteousness is full of flaws! Look to Him; boast in Him; and men shall come to you for your secret. [source]
Chapter Summary: Isaiah 45
1God calls Cyrus for his church's sake 5By his omnipotence he challenges obedience 20He convinces the idols of vanity by his saving power
What do the individual words in Isaiah 45:22 mean?
Lookto Meand be savedallyou endsof the earthforI [am]Godand [there is] noother